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GALLERY: Hsv 2

HSV-2 Swift is a hybrid catamaran . She was privately owned and operated by Sealift Inc. , and was originally built under the JHSV program as a proof of concept . As part of this program, she was directly leased for evaluation from her builders by the United States Navy Military Sealift Command from 2003 to 2013, primarily as a mine countermeasures and sea basing test platform. Later during her official naval career she was mostly used for fleet support and humanitarian partnership missions.

Herpes simplex virus 1 and 2 ( HSV-1 and HSV-2 ), also known as human herpesvirus 1 and 2 ( HHV-1 and HHV-2 ), are two members of the herpesvirus family, Herpesviridae , that infect humans . [1] Both HSV-1 (which produces most cold sores ) and HSV-2 (which produces most genital herpes) are ubiquitous and contagious . They can be spread when an infected person is producing and shedding the virus .

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  • File:HSV 2 Swift.jpg - Wikipedia, the free encyclopedia
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In the case of a herpes virus, initial interactions occur when two viral envelope glycoprotein called glycoprotein C (gC) and glycoprotein B (gB) bind to a cell surface particle called heparan sulfate. Next, the major receptor binding protein, glycoprotein D (gD), binds specifically to at least one of three known entry receptors. These cell receptors include herpesvirus entry mediator (HVEM), nectin-1 and 3-O sulfated heparan sulfate. The nectin receptors usually produce cell-cell adhesion, to provide a strong point of attachment for the virus to the host cell. These interactions bring the membrane surfaces into mutual proximity and allow for other glycoproteins embedded in the viral envelope to interact with other cell surface molecules. Once bound to the HVEM, gD changes its conformation and interacts with viral glycoproteins H (gH) and L (gL), which form a complex. The interaction of these membrane proteins may result in a hemifusion state. gB interaction with the gH/gL complex creates an entry pore for the viral capsid. gB interacts with glycosaminoglycans on the surface of the host cell.

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  • Description Hsv-2swiftrear343.jpg
  • ... Two (HSV-2) Swift glides through the waters of the Atlantic Ocean.jpg
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  • ... (HSV-2) Swift arrives in Pearl Harbor for routine maintenance.jpg
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